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September 2017
Public Access

Category: All

	Sun	Mon	Tue	Wed	Thu	Fri	Sat
W K 3 5	27	28	29	30	31	01	02
W K 3 6	03	04	05 09:00 - 18:00» Hellenic Bioinformatics 10 â€¢ 2017	06 09:00 - 18:00» Hellenic Bioinformatics 10 â€¢ 2017	07 09:00 - 18:00» Hellenic Bioinformatics 10 â€¢ 2017	08 09:00 - 18:00» Hellenic Bioinformatics 10 â€¢ 2017	09
W K 3 7	10	11	12	13	14 12:00» UOC Seminar Kathryn Melzak 16:00 - 17:00» MST colloquium	15 15:00 - 16:00» IMBB SEMINAR	16
W K 3 8	17	18 12:00 - 13:00» CHEMISTRY SEMINAR	19 12:00 - 13:00» IMBB SEMINAR 14:00 - 15:00» CHEMISTRY SEMINAR	20 14:00 - 15:00» FORTH SEMINAR	21	22 12:00 - 14:00» IMBB SEMINAR	23
W K 3 9	24	25	26 11:30 - 12:30» Î ÏÏŒÏƒÎºÎ»Î·ÏƒÎ· Ï€Î±ÏÎ¿Ï…ÏƒÎ¯Î±ÏƒÎ·Ï‚ Î´Î¹Î´Î±ÎºÏ„Î¿ÏÎ¹ÎºÎ®Ï‚ Î´Î¹Î±Ï„ÏÎ¹Î	27	28 16:00 - 17:00» MST colloquium	29 18:00 - 22:00» Î’ÏÎ±Î´Î¹Î¬ Î•ÏÎµÏ…Î½Î·Ï„Î® 2017	30

TASKS
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Time:: 16:00 - 17:00
Location:: Computer Science Department, room A115 (ground floor), Voutes
Description:: Thursday, September 14, 2017

Speaker: Dr. Sotirios Korossis

Affiliation: Lower Saxony Centre for Biomedical Engineering Implant
Research and Development Department of Cardiothoracic, Transplantation &
Vascular Surgery,
Hannover Medical School

Title: From the Heart to the Lung and Back: Engineering the Path

Location: Computer Science Department, room A115 (ground floor), Voutes

Time: 16:00

Language: English

Abstract

Cardiovascular and pulmonary diseases are the leading causes of
morbidity and mortality, being among the top 3 diseases in terms of
healthcare spending worldwide. Valve replacement or repair is the 2nd
most common major heart operation in the western world, whereas vascular
stenting represents one of the most commonly performed procedures for
treating occlusive coronary artery disease. Moreover, lung
transplantation still remains the only viable option for the treatment
of patients with end-stage lung diseases, such as chronic obstructive
pulmonary disease (COPD), with extracorporeal membrane oxygenation
(ECMO) representing the current clinical practice as a bridge to
transplantation.
Currently, synthetic biomaterials chemically cross-linked animal or
human donor tissues are most commonly used for cardiovascular tissue
repair or replacement. However, conventional approaches only deliver
inert or biocompatible material solutions that prevent cellular
migration after implantation and cannot regenerate or grow with the
patient. Surgeons prefer autologous tissue since it will retain
viability and regenerate. However, autologous tissue is limited or not
available at all. Tissue engineering offers an attractive alternative
for cardiovascular tissue reconstructions, aiming to develop
tailor-made, functional substitutes for implantation, with the purpose
of fostering remodelling and regeneration of diseased tissue.
In the case of ECMO, the use of oxygenator devices is limited to a few
weeks due to contact of the patientÊ¼s blood with the artificial
components of the device, and the consequent thrombus formation and
deposition of blood components within the device. The improvement of the
haemocompatibility of current ECMO devices does not only have the
potential to prolong ECMO usage in anticipation of a suitable lung
transplant, but it can also provide a destination therapy, as an
alternative to lung transplantation. To this end, surface
endothelialization has been considered an effective approach to enhance
long-term haemocompatibility of blood-contacting devices, such as
circulatory assist devices and stents.
This seminar will present an overview of the work undertaken at Hannover
Medical School in the fields of valvular tissue engineering and
biohybrid devices, including artificial lung and stents.

Host: Anna Mitraki 4095

Time:: 16:00 - 17:00
Location:: Computer Science Department, room A115 (ground floor), Voutes
Description:: Thursday September 28, 2017

Speaker: Dr. Jack F. Douglas

Affiliation: National Institute of Standards and Technology, Materials Science and Engineering Division, Gaithersburg, MD 20899 USA

Title: â€œCooperative Motion and Structural Relaxation in Glass-Forming Materialsâ€

Location: Computer Science Department, room A115 (ground floor), Voutes

Time:16:00

Language:English

Abstract
We investigate collective motion and relaxation in model polymeric glass-forming liquids by molecular dynamics simulation to quantify the
nature of cooperative motion in these liquids and to understand the significance of cooperative particle exchange motion for understanding relaxation properties of glass-forming liquids generally. We find that
relaxation occurs as multi-stage process involving cooperative molecular motion. First, there is a â€˜fastâ€™ or b-relaxation process dominated by the inertial motion of the molecules, followed by a longer time
a-relaxation process involving large scale diffusive motion. Our molecular dynamics simulations indicate that as the collective motion of the b-relaxation regime becomes progressively suppressed upon approaching Tg, material relaxation requires larger scale collective motion involving molecular diffusion, explaining the emergence of the a-relaxation regime. In both relaxation regimes, relaxation occurs through a string-like collective particle exchange motion having a common string-like geometrical form and quantitative relationships are derived relating the length of the â€˜stringletsâ€™ found in the b-relaxation regime to the â€˜stringsâ€™ characterizing collective motion at long times associated with the thermally activated diffusive motion. Based on this physical picture, we find that the a-relaxation time data for a wide range of simulated glass-forming liquids can be described by an extension of the Adam-Gibbs model in which the free energy of activation (including the entropy of activation neglected by AG) is proportional to the average length L of string-like particle exchange clusters. This same type of collective motion arises in the grain boundaries of polycrystalline materials, the interfaces of
nanoparticles, superheated crystals, and in biological materials such lipid membranes and proteins so that string-like collective motion is evidently a common feature of strongly-interacting condensed matter.

Host: Dimitris Vlassopoulos