Argyris PAPANTONIS
Group leader
Center for Molecular Medicine Cologne
University of Cologne
Title: "Genomic 3D reorganization in homeostasis and senescence"
Monday, January 29th, 2018 @ 12:00
Main Amphitheater “G. Lianis”, FORTH’s bldg
Host: G. Garinis
Time:
16:00 - 17:00
Location:
Seminar Room 1, FORTH’s bldg
Description:
Announcement – IMBB Chromatin Club
Dear All,
The first meeting of the IMBB Chromatin Club will be organized at 16.00
in January 29, 2018 (Seminar Room 1, FORTH’s bldg). Everybody interested
are welcome to participate in this discussion forum.
The topic of the first meeting will be:
“Genome organization in the nucleus: from worms to humans”
The discussion will be moderated by I. Talianidis, C. Spilianakis and A.
Papantonis.
We advise the attendance of the IMBB Seminar given by A. Papantonis
earlier the same day.
The use of oil-in-water emulsions for controlled lipid release is of increasing relevance for poorly water-soluble drugs and gained major
interest for treating obesity. In this conceptual study, we highlight
the relevance of interfacial rheology combined with neutron reflectivity measurements in designing emulsion systems with stimuli-responsive biopolymers to generate specific lipid digestion kinetics.
Stimuli-responsive biopolymers change their mechanical and emulsion stabilization properties at specific physicochemical conditions present
in the human environment. We used whey protein isolate because of its sensitivity to pH, methylcellulose because of its sensitivity to
temperature, and nanocrystalline cellulose because of its sensitivity to ionic strength [1]. The biopolymer-dependent effects on gastric
lipolysis and gastric emulsion structuring, more precisely droplet size and viscosity, during digestion and resulting pancreatic lipolysis was
investigated in-vitro. In order to establish a valid in-vitro/in-vivo correlation, emulsion structures formed during gastric digestion
in-vitro were validated by in-vivo magnetic resonance imaging experiments visualizing emulsion structuring and stomach emptying [2].
In parallel, in-vivo lipid sensing and release patterns were investigated by repetitive measurements of measuring plasma
triglycerides and cholecystocinin concentrations in healthy human volunteers. By taking all relevant physicochemical and mechanical
processes of human digestion into account, we are thus able to propose design concepts for food and drug delivery systems [3].
[1] Scheuble N, Lussi M, Geue T, Carrière F, Fischer P:
Biomacromolecules 17 (2016) 3328.
[2] Steingoetter A, Buetikofer S, Curcic J, Menne D, Rehfeld JF, Fried
M, Schwizer W, Wooster TJ: J. Nutrit. 147 (2017) 706.
[3] Scheuble N, Schaffner J, Schumacher M, Windhab EJ, Liu D, Parker H,
Steingoetter A, Fischer P: submitted
Host: Dimitris Vlassopoulos 1469
For forthcoming colloquia, please see:
https://www.materials.uoc.gr/el/colloquia
Time:
12:00 - 13:00
Location:
“Seminar Room 1”, FORTH’s bldg
Description:
IMBB JOINT COLLOQUIA
Angeliki VOGIATSI (Mavrothalassitis Lab)
Title:
Time:
12:00 - 13:00
Location:
Main Amphitheater “G. Lianis”, FORTH’s bldg
Description:
IMBB JOINT COLLOQUIA
Ourania GALANOPOULOU (Talianidis Lab)
Title: "Endonucleosis: an unusual autophagy process causing cellular
senescence and necrotic death"
Shane DENECKE (Vontas Lab)
Title: "Understanding the Genetics of Pharmacokinetics Using Model Organisms"
Friday, March 2nd, 2018 @ 12:00
Main Amphitheater “G. Lianis”, FORTH’s bldg
Time:
13:00
Description:
Sofia Giarmatziadi
A QCM-D study of the interactions of intercalating molecules with DNA
Supervisor: Prof.,I. Gizeli
Friday 2 March 2018 @ 13:00
Teleconference room, Biology Dept.