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| Description: | Hans BRÜCKNER (Univ. Giessen) Peptaibiomics: From Fungal Biodiversity to Membrane-active Polypeptides and Peptide Drugs Seminar room 1 host: Kyriakos Petratos Abstract: Amphipathic fungal polypeptides containing the non-protein amino acid alpha-aminoisobutyric acid (Aib) are unique with regard to an abundance of bioactivities comprising antibiotic and transmembrane-channel forming properties. For these peptides the acronym 'peptaibiotics' has been proposed, meaning peptides containing Aib and showing biotic activities. Owing to their non-ribosomal synthesis by megaenzymes, an array of peptides is produced simultaneously. Determination of the entirety of structures in the course of the synthesis is the subject of peptaibiomics. |
| Status: | Waiting for approval |
| Date: | Friday, August 31, 2012 |
| Time: | 12:00 EEST |
| Priority: | 5-Medium |
| Access: | Public |
| Created by: | Lila Kalogeraki |
| Updated: | Wednesday, August 29, 2012 09:17 GMT |