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| Description: | Τίτλος: Natural selection on autosomal and X-linked genes in mice and implications for speciation genetics. Ομιλητής: Θανάσης Κουσαθανάς University of Edinburgh Περίληψη: Evolutionary biologists have documented a special role of the X chromosome in speciation: loci that contribute to the evolution of reproductive isolation between species are located disproportionally on the X chromosome compared to the autosomes. An evolutionary explanation for this puzzling phenomenon has long been sought. One compelling hypothesis states that the X chromosome evolves faster than the autosomes, because new advantageous mutations are on average recessive. According to this hypothesis, recessive mutations are exposed to selection on the X chromosome in males and are driven to fixation at a faster rate than the autosomes. To test this hypothesis, I compared the rate of adaptive substitution in autosomal versus X-linked protein-coding genes in a subspecies of the house mouse. I found that the X chromosome does experience a faster rate of adaptive substitution than the autosomes, which is more pronounced for genes that are specifically expressed in male reproductive tissues. This finding suggests that faster-X evolution could at least partially explain the large effect of the X chromosome in speciation. Χρόνος: Τετάρτη 26/6/2013, ώρα: 11:00 πμ Xώρος: Αμφιθέατρο Β, Τμήμα Βιολογίας. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Emmanuel (Manolis) LADOUKAKIS, M.Sc., Ph.D. Department of Biology University of Crete Voutes University Campus 70013 Heraklio Greece Tel: +30 2810 394067 |
| Status: | Waiting for approval |
| Date: | Wednesday, June 26, 2013 |
| Time: | 11:00 EEST |
| Priority: | 5-Medium |
| Access: | Public |
| Created by: | Lila Kalogeraki |
| Updated: | Tuesday, June 25, 2013 08:07 GMT |