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| Description: | Vassilis CUTSURIDIS Poirazi's Lab Title: "Encoding and Consolidation of Memories in the Rodent Hippocampus". Friday, January 24th 2013 @ 12:00 Seminar Room 1 [FORTH's bldg] Abstract -------- The rodent hippocampus is one of the most studied brain regions. The hippocampus plays an important role in the encoding, retrieval and consolidation of spatial and episodic memories. Although much is known about the anatomical, physiological and molecular characteristics as well as the connectivity and synaptic properties of various cell types in the hippocampal microcircuits, how these detailed properties of individual neurons give rise to the encoding, retrieval and consolidation of memories remains unclear. Computational models play an instrumental role in providing clues on how these processes may take place. In this talk, I will present three computational models of the region CA1 of the hippocampus at various levels of detail (Cutsuridis et al. (2010) Hippocampus 20(3): 423-446; Cutsuridis and Hasselmo (2012) Hippocampus 22: 1597-1621; Saravanan et al., under review). Issues such as memory capacity, recall performance, memory replay, and phase precession during various brain rhythms and in the presence of neuromodulation and various types of inhibitory interneurons will be addressed. My models lead to a number of experimentally testable predictions that may lead to a better understanding of the biophysical computations in the rodent hippocampus. |
| Status: | Waiting for approval |
| Date: | Friday, January 24, 2014 |
| Time: | 12:00 EET |
| Priority: | 5-Medium |
| Access: | Public |
| Created by: | Lila Kalogeraki |
| Updated: | Monday, January 20, 2014 09:08 GMT |