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UOC Seminar Kathryn Melzak

Description: Dr Kathryn Melzak
Institute for Functional Interface (IFG), KIT, Karlsruhe, Germany
Red blood cell storage and the effects of diethylhexylphtalate (DEHP) plasticizer
Abstract
Bags used to store blood for transfusions contain the plasticiser diethylhexylphthalate (DEHP). The DEHP is regarded as a potential toxin, and is on EU lists of chemicals to be restricted. One challenge with finding an alternate plasticiser is that the DEHP has a beneficial effect, improving the quality of the stored RBCs; replacements will therefore have to have similar effects in order to maintain the standards of the blood supply. The mechanism by which DEHP exerts its effects is unknown. The work presented here is about the interaction of the DEHP with the RBC membrane, with some comments on how this can affect the RBC shape during storage.

Date: 14/9/2017

Time:12:00 (coffee & cookies will be served at 00:00)

Place: FORTH Seminar Room 1
Location: FORTH Seminar Room 1
Status: Waiting for approval
Date: Thursday, September 14, 2017
Time: 12:00 EEST
Priority: 5-Medium
Access: Public
Created by: Lila Kalogeraki
Updated: Wednesday, September 13, 2017 08:32 GMT