“IFN-I directly acts on T lymphocytes resulting in milder development of the early phases of the EAE”
Wednesday 1/10/2014, 1:00 pm
Room 7A.02, Med School
Info: G. Mavrothalassitis x 4537
Time:
15:00
Description:
Dr. Ioanna TRIVIAI
Junior Group Leader - Stem Cell Biology Group
Clinic of Stem Cell Transplantation, University Medical Center Hamburg
Eppendorf, Hamburg, Germany
And Heinrich – Pette Institut, Leibniz Institute for Experimental Virology, Hamburg, Hamburg, Germany
Title: "Neoplastic stem cells in hematopoietic niche disruption: the paradigm of Primary Myelofibrosis".
ABSTRACT:
Myeloproliferative neoplasms (MPN) are chronic hematological malignancies characterized by expansion of aberrant myeloid progenitors.
Primary myelofibrosis (PMF) has the worst prognosis of all MPN and involves massive disruption of the hematopoietic niche leading to fibrosis/osteosclerosis development and/or transformation to acute myeloid leukemia (AML). In our studies to elucidate the trigerring event in PMF we identified a neoplastic stem cell population in patient peripheral blood responsible for disease initiation and development in vivo. Identifying the neoplastic stem cells in myeloproliferating neoplasms will provide the basis to decipher complicated niche
interactions implicated in evolution of the chronic phase and leukemic transformation and introduce new therapeutical targets to eradicate the disease.
Emmanouil G. Spanakis, PhD.
Computational Medicine Laboratory
Institute of Computer Science
Time:
12:00
Description:
SPEAKER: Prof. Anastasios Melis,
University of California, Berkeley
Dept. of Plant & Microbial Biology
111 Koshland Hall
Berkeley, CA 94720-3102
http://pmb.berkeley.edu/profile/amelis
TITLE: " Photosynthesis for fuel and chemicals production"
DATE: Friday 3rd October 2014
TIME: 12:00
ROOM: Chemistry Seminar Room
Time:
13:00-14:00
Description:
Genetic Dissection of Death Receptor Signalling
Carlos F. Ibáñez
Professor of Neuroscience, Karolinska Institute
& Neurobiology Programme, National University of Singapore