BioMicroElectroMechanical Systems (Bio-MEMS) is an emerging technology
that aims to provide miniaturized, sophisticated, clinical devices and
research tools to the life science community. In this talk, I will
describe two such novel micro-technologies: (i) a new generation of
microfluidic devices that can manipulate whole micro-organisms (such as
the worm C. elegans) and image in vivo their neuronal responses at the
single neuron level. Functional imaging data from aged neurons from C.
elegans indicate, for the first time, that neural degradation is
affected by aging. These microfluidic devices can be further automated
for use in high-throughput anti-aging drug screening applications, and
(ii) a portable, Bio-MEMS platform for monitoring HIV-infected patients
in resource-limited settings. Such a platfrom can reach the end-user
wherever limited infrastructure is present and no access to a hospital
or clinic is possible. The proposed technology will not only make it
possible to monitor the efficacy of an individual’s therapy in the
developing world, but it will make more medicines available by
identifying patients who need a treatment from patients who do not need
it.
Host: Anna Mitraki 4095
Time:
13:00-14:00
Location:
“Seminar Room 1”, FORTH’s bldg
Description:
IMBB SEMINAR
Christoforos NIKOLAOU
Assistant Professor
Department of Biology
University of Crete
Title: "Chromatin Structure and Transcriptional Activity shaping Genomic Landscapes in Eukaryotes"