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Friday, March 14, 2014
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TASKS +
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12:00 [12:00] IMBB Seminar
Description:
Jorgen KJEMS Director of Interdisciplinary Nanoscience Center (iNANO) Director of Lundbeck Nanomedicine Center (LUNA) Interdisciplinary Nanoscience Center (iNANO) Department of Molecular Biology and Genetics Aarhus University, Denmark "The expanding family of non-coding RNAs – increasing complexity of gene regulation and new opportunities in nano medicine". Friday, March 14th 2014 @ 12:00 Seminar Room 1 [FORTH's bldg] Host: E. Gizeli -------------------------------------------------- Seminars will also become available for watching at IMBB's YouTube Channel: http://www.youtube.com/channel/UCPeRZVC0qvjFt83jDtYTyqA

13:00 [13:00-14:00] Seminar in Neuroscience
Description:
Silvia Lisa Ferrer, PhD Instituto de Quimica-Fisica Rocasolano Madrid Spain « Molecular switches in the genesis of pathogenic PrP: methionilsulfoxides and their models » Friday, March 14 2014 13.00-14.00 Room 7A 02 Graduate Studies Building School of Medicine University of Crete (for info contact K. Thermos x4533) Abstract Molecular switches in the genesis of pathogenic PrP: methionilsulfoxides and their models Prion disorders are dominant gain-of-function neurodegenerations whose pathogenesis is linked to misfolded forms of the cellular prion protein (PrPC), including the prion PrPSc and the neurotoxic CtmPrP (1-4). PrPSc is an aggregated and protease resistant β-sheet-enriched conformer of PrPC, which self-perpetuates by the templating the conversion of cell surface PrPC (1,4). In contrast, CtmPrP is an intracellular transmembrane form generated at the ER with neurotoxic properties (1,5,6). The long-standing hypothesis of prion biology is that the distinct biological and physicochemical properties separating PrPC and PrPSc relate only to the conformational differences of the C-terminal domain, which adopts a major globular α-fold in PrPC and displays a high content of β-sheet structure in PrPSc (7,8). However, the populations of PrPC and PrPSc also differ in the redox state the methionines of Helix-3, suggesting a possible role for these residues in facilitating the structural change ADDIN EN.CITE

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16:00 [16:00] MST colloquium
Description:
Friday, March 14th, 2014 Speaker Emmanuel Kymakis Affiliation Center of Materials Technology & Photonics, Electrical Engineering Department, TEI of Crete Title Organic Photovoltaics Engineering Location Department of Physics Bldg., Voutes, 3rd floor Seminar Room Time 16:00 Language English Abstract Organic photovoltaics (OPVs) are among the most promising photovoltaic technologies for long term sustainable energy production. The low-temperature solution processability allows for roll-to-roll mass production on flexible plastic substrates which is expected to lead to a light-weight and low-cost energy production platform, particular attractive for off grid and small power consumer electronics applications. In this talk, I will briefly report our recent efforts on solution processable graphene (SPG) materials development and plasmonic device engineering to significantly enhance the performance and stability of OPVs. SPG based materials have been utilized as various components in OPVs, including transparent electrodes, buffer and active layers. In particular, functionalized SPG derivatives, synthesized via efficient functionalization of graphene oxide (GO) using conventional chemical modification routes, are utilized as the electron acceptor material or additive in OPVs. Highly transparent and conductive reduced GO (rGO) films on solid and flexible substrates are utilized as the transparent electrodes. The electrodes are produced in situ, by laser assisted photothermal reduction of spin casted GO films. In the same way, doped GO films with tuned work-function are produced by photochlorination. As a proof of concept, highly efficient OPVs, incorporating photochlorinated GO as the buffer layer material are successfully demonstrated, significantly outperforming the reference PEDOT:PSS and pristine GO devices. In the second part of my talk, I will address recent advances in the rapidly developing field of plasmonic organic photovoltaics. NPs of various sizes, shapes and configurations have been integrated into OPV cell architecture in order to tune and enhance, in a wavelength-dependent manner, the optical absorption of the respective devices. As a result impressive improvements in the respective device efficiencies were achieved. Particular attention will be paid in our work on the incorporation of uncapped Au, Ag and Al NPs formed by ablation of metallic targets in liquids with pico- and femtosecond laser pulses in the active layer leading to a significant enhancement in both device performance and lifetime

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