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[16:00] MST Colloquium
- Description:
- Speaker: Dr. Efstathios Kaliviotis
Affiliation: Department of Mechanical Engineering and Materials Science
and Engineering, Cyprus University of Technology,
Dept. of Mechanical Engineering, University College London, UK
Title: “Blood rheology and flow characteristics in the macro- and
micro-scale”.
Location: Computer Science Department, room A115 (ground floor), Voutes
Time: 16:00
Language: English
Abstract
Blood can be considered as a two phase, non-Newtonian fluid, and its
flow characteristics, in particular in the microvasculature, are
affected by this fact. To a large degree the complex mechanical nature
of the fluid is due to red blood cell (RBC) aggregation phenomenon,
which is found intense in a number of pathological conditions. The time
and flow-dependent characteristics of the aggregated structures
developed in blood affect its mechanical properties, and can be examined
by various techniques. In this talk the influence of RBC aggregation on
blood rheology at the macroscale will be discussed first. It will be
shown that secondary aggregation characteristics may play a key role in
explaining the behaviour of the mechanical properties of the fluid under
various flow conditions. Secondly, the influence of the RBC aggregation
phenomenon on the flow characteristics for microscale bifurcating
geometries, resembling the microvasculature, will be discussed. It will
be illustrated that the aggregation phenomenon, apart from the flow
characteristics, affects the aggregate distribution in the bifurcation
in a counterintuitive manner, i.e. the smaller aggregates appear in
regions of lower shear, as opposed to the general understanding that
aggregation increases at the specific shear conditions. Such behaviour
is explained when considering the spatial distribution of aggregates in
conjunction to the velocity field developed in the parent channel
branches. Finally, an attempt to predict the local viscosity in the
microchannels will be described based on existing constitutive equations
for blood.
Host: Dimitris Vlassopoulos 1469
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November 2017
